How to run a Kinase Binding Platform assay Multiple signal transduction pathways, one analysis platform Kinases are one of the most widely investigated drug target classes, with over 20 years in the spotlight for drug discovery.

The LanthaScreen TM Eu Kinase Binding assay platform (ThermoFisher Scientific) was designed as an HTS platform that can identify any compound that alters binding to the active site (aka ATP-site) on a kinase. The platform employs a fluorescently labeled t

assays quantitatively measure the binding of small molecules to the ATP. KINASE PROFILING & SCREENING . Choosing a Biochemical Assay Platform INTRODUCTION Protein kinases have emerged as a major drug target over the past two decades. Since 2001, over