Adaptive designs can make clinical trials more flexible by utilising results accumulating in the trial to modify the trial’s course in accordance with pre-specified rules. Trials with an adaptive design are often more efficient, informative and ethical

I believe the broad field of immuno-metabolism will ultimately benefit from lessons learned. Many have written about the specifics of the trial design; so rather, I will focus my initial reactions on why I remain bullish on targeting IDO1/TDO biology as a

LESSONS LEARNED AND WAYS FORWARD Markus keck and Patrick sakdaPolrak With 1 table Received 09. November 2012 · Accepted 20. March 2013 Summary: Over the last decade, a growing body of literature has emerged which is concerned with the question of what fo