Review these 3 general guidelines for use, preparing, and dosing Cathflo® Activase® (alteplase). Do not forget to reconstitute Cathflo® immediately before use. See full safety for more information.

If catheter function is not restored at 120 minutes after 1 dose of Cathflo Activase, a second dose may be instilled (see Instructions for Administration).There is no efficacy or safety information on dosing in excess of 2 mg per dose for this indication.

Cathflo®: Non-stopcock method Page 2 of 2 10. Again assess catheter patency by attempting to aspirate blood. 11. If catheter patency has been restored, aspirate 4-5 ml of blood to remove Cathflo® and the