Dry DMF can be prepared by drying overnight over barium oxide or 4A molecular sieves, followed by decantation of the drying agent and vacuum distillation (~20 mmHg is a sufficient vacuum to lower the boiling point over DMF to a reasonable value). Dry DMF

Air dry the molecular sieve from empty solvent bottles in a fume hood draft until they appear dry before heating at elevated temperatures. While the sieves bind much water, they also hold some solvent and you don't want to heat the pellets very hot wi

suggest drying over 4A molecular sieves for 24h or drying over CaH and subsequent distillation. When using a hydride for drying purposes be sure to have inert atmosphere in your still to prevent ...